A Double-Edged-Sword Approach to Fighting Pandemics: Patent Waivers and Incentives to Innovate

“A Patent Waiver on Covid Vaccines Is Right and Fair.” Nature 593, no. 7860 (2021): 478. https://doi.org/https://doi.org/10.1038/d41586-021-01242-1. (Crossref)

“Advance Purchase Agreement (‘APA’)1 for the Development, Production, Ad¬vance Purchase and Supply of a COVID-19 Vaccine for EU Member States (SANTE/2020/C3/049).” European Commission, Directorate-General for Health and Food Safety, 2020.

Agüero, Montserrat, Isabella Monne, Azucena Sánchez, Bianca Zecchin, Alice Fusaro, María José Ruano, Manuel del Valle Arrojo, Ricardo Fernández-An¬tonio, Antonio Manuel Souto, Pedro Tordable, Julio Cañás, Francesco Bonfante, Edoardo Giussani, Calogero Terregino, and Jesús Javier Orejas. “Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in Farmed Minks, Spain, October 2022.” Eurosurveillance 28, no. 3 (2023). https://doi. org/10.2807/1560-7917.es.2023.28.3.2300001. (Crossref)

All European Academies. “Allea statement on vaccination bottlenecks in the Global South and a patent waiver for the COVID-19 vaccines.” Accessed September 14, 2023. https://www.wto.org/english/tratop_e/covid19_e/al¬lea_letter_e.pdf.

Amnesty International. “G7 Leaders Are Failing to Tackle Global Vaccine Ac¬cess.” August 8, 2022. https://www.amnesty.org/en/latest/news/2021/02/g7- leaders-are-shooting-themselves-in-the-foot-by-failing-to-tackle-global-vaccine-access .

Anderson, Michael, Rebecca Forman, and Elias Mossialos. “Navigating the Role of the EU Health Emergency Preparedness and Response Authority (HERA) in Europe and Beyond.” The Lancet Regional Health – Europe 9 (2021): 100203. https://doi.org/10.1016/j.lanepe.2021.100203. (Crossref)

Bavel, Jay J., Katherine Baicker, Paulo S. Boggio, Valerio Capraro, Aleksandra Ci¬chocka, Mina Cikara, Molly J. Crockett, et al. “Using Social and Behavioural Science to Support COVID-19 Pandemic Response.” Nature Human Behav¬iour 4, no. 5 (2020): 460–71. https://doi.org/10.1038/s41562-020-0884-z. (Crossref)

Bennett, Matthew, and Philip Collins. “The Law and Economics of Information Sharing: The Good, the Bad and the Ugly.” European Competition Journal 6, no. 2 (2010): 311–37. https://doi.org/10.5235/174410510792283754. (Crossref)

Beuker, Mark. “Combining Legal and Economic Theory. An Interdisciplinary Approach to Dutch and Polish Family Provisions in Succession Law.” Re¬view of European and Comparative Law 47, no. 4 (2021): 49–65. https:// doi.org/10.31743/recl.12840. (Crossref)

Boldrin, Michele, and David K. Levine. “Should Patents on Covid-19 Vaccines Be Waived?.” Science, Technology and Innovation, 2021.

Brown, David. “Vaccine Would Be Spoken for Rich Nations Have Pre-Existing Contracts.” The Washington Post. May 7, 2019. https://www.washingtonpost. com/wp-dyn/content/article/2009/05/06/AR2009050603760.html.

Capobianco, Antonio. “Information Exchange under EC Competition Law.” Common Market Law Review 41, no. 5 (2004): 1247–76. https://doi. org/10.54648/cola2004047. (Crossref)

Cooter, Robert, and Hans-Bernd Schäfer. Solomon’s Knot: How Law Can End the Poverty of Nations. Princeton: Princeton University Press, 2012. (Crossref)

Cooter, Robert, and Thomas Ulen. Law and Economics. Harlow: Pearson Edu¬cation, 2014.

Council for TRIPS. “Waiver from Certain Provision of the TRIPS Agreement for the Prevention, Containment, and Treatment of COVID-19 (IP/C/W/669).” World Trade Organisation, 2020.

Cozzi, Guido. “Shall We Fear a Covid-19 Patent Waiver?.” SSRN Electronic Jour¬nal, 2022. https://doi.org/10.2139/ssrn.4015067. (Crossref)

Damiani, Anne, and Giedre Peseckyte. “EU Countries Are Throwing Away Expired Vaccine Doses.” EURACTIV, July 29, 2021. https://www.eurac¬tiv.com/section/coronavirus/news/eu-countries-are-throwing-away-ex¬pired-vaccine-doses/.

Darrow, Jonathan J., Michael S. Sinha, and Aaron S. Kesselheim. “When Markets Fail: Patents and Infectious Disease Products.” Food & Drug L J 73, no. 3 (2018): 361–382.

De Geest, Gerrit. Contract Law and Economics – Encyclopaedia of Law and Eco¬nomics, vol. 6, 2 ed. Cheltenham: Edward Elgar, 2011. (Crossref)

Duckett, Adam. “What Is Causing AstraZeneca’s Vaccine Production Woes?.” The Chemical Engineer, 2021.

European Commission. “Coronavirus: Commission Approves Contract with Valneva to Secure a New Potential Vaccine.” September 22, 2020. https:// ec.europa.eu/commission/presscorner/detail/en/QANDA_20_1662.

European Commission. “EU Vaccine Strategy.” Accessed March 21, 2022. https:// commission.europa.eu/live-work-travel-eu_en.

European Commission. “Pharmaceutical Sector Inquiry Final Report,” 2019.

European Commission. “Questions and Answers: Coronavirus and the EU Vaccines Strategy.” September 24, 2020. Accessed March 20, 2022. https:// ec.europa.eu/commission/presscorner/detail/en/QANDA_20_1662.

Fox, Harold G. Monopolies and Patents: A Study of the History and Future of the Patent Monopoly. Toronto: The University of Toronto Press, 1947. (Crossref)

Frankel, Alexander, Joshua Krieger, Danielle Li, and Dimitris Papanikolaou. Evaluation and Learning in R&D Investment, 2023. https://doi.org/10.3386/ w31290. (Crossref)

Fregonese, Laura, Lesley Greene, Matthias Hofer, Armando Magrelli, Frauke Naumann-Winter, Kristina Larsson, Maria Sheean, Violeta Stoyanova-Be¬ninska, Stelios Tsigkos, Kerstin Westermark, and Bruno Sepodes. “Demon¬strating Significant Benefit of Orphan Medicines: Analysis of 15 Years of Ex¬perience in Europe.” Drug Discovery Today 23, no. 1 (2018): 90–100. https:// doi.org/10.1016/j.drudis.2017.09.010. (Crossref)

Gammie, Todd, Christine Y. Lu, and Zaheer Ud-Din Babar. “Access to Orphan Drugs: A Comprehensive Review of Legislations, Regulations, and Policies in 35 Countries.” PLOS ONE 10, no. 10 (2015). https://doi.org/10.1371/jour¬nal.pone.0140002. (Crossref)

Gurgula, Olga, and John Hull. “Compulsory Licensing of Trade Secrets: Ensur¬ing Access to COVID-19 Vaccines via Involuntary Technology Transfer.” Journal of Intellectual Property Law & Practice 16, no. 11 (2021): 1242–61. https://doi.org/10.1093/jiplp/jpab129. (Crossref)

Gurgula, Olga, and Wen Hwa Lee. “Covid-19, IP and Access: Will the Current System of Medical Innovation and Access to Medicines Meet Global Expec¬tations?.” SSRN Electronic Journal (2021): 61–70. https://doi.org/10.2139/ ssrn.3771935. (Crossref)

Hall, Bronwyn H., and Nathan Rosenberg. Handbook of the Economics of Innova¬tion. Amsterdam: North Holland, 2010.

Henley, Jon. “AstraZeneca Did ‘not Even Try’ to Meet Covid Vaccine Contract, EU Tells Court.” The Guardian, 26 May 2021. https://www.theguardian.com/ world/2021/may/26/eu-seeks-court-order-for-astrazeneca-to-supply-vac¬cine-doses.

IP/c/w/680 Council for trade-related aspects of intellectual property. Accessed September 14, 2023. https://docs.wto.org/dol2fe/Pages/SS/directdoc.aspx?¬filename=q:/IP/C/W680.pdf&Open=True.

Johnson, Eric E., and Theodore C. Bailey. “Urgent Legal Lessons from a Very Fast Problem: COVID-19.” Stanford Law Review 73 (2020): 89–103. https:// doi.org/https://ssrn.com/abstract=3567412.

Kovac, Mitja, and Lana Rakovec. “The COVID‐19 Pandemic and Long‐term In¬centives for Developing Vaccines: Patent Law under Stress.” The Journal of World Intellectual Property 25, no. 2 (2022): 292–316. https://doi.org/10.1111/ jwip.12223. (Crossref)

Kovac, Mitja, and Patricia Kotnik. “Self-Assessment System: Detrimental Effects upon Entrepreneurial and Innovative Activity.” SSRN Electronic Journal, 2013. https://doi.org/10.2139/ssrn.2221811. (Crossref)

Kupferschmidt, Kai. “‘Incredibly Concerning’: Bird Flu Outbreak at Spanish Mink Farm Triggers Pandemic Fears.” Science, 24 January 2023. https://www. science.org/content/article/incredibly-concerning-bird-flu-outbreak-span¬ish-mink-farm-triggers-pandemic-fears.

LaHucik, Kyle. “BioNTech to Start Building Mrna Vaccine Manufacturing Plant in Africa in Mid-2022.” Fierce Pharma, October 26, 2021. https://www.fier¬ cepharma.com/manufacturing/biontech-to-build-mrna-vaccine-manufac¬turing-plant-africa-mid-2022-plans-finalised.

Lester, Simon, Bryan Mercurio, and Arwel Davies. World Trade Law Text, Ma¬terials, and Commentary. Oxford, London, New York, New Delhi, Sydney: Hart Publishing, 2018.

Love, James. “President and Minister of Health of Costa Rica Ask Who to Create Global Pool for Rights in COVID-19 Related Technologies.” Knowledge Ecol¬ogy International, March 24, 2020. https://www.keionline.org/32556.

Machado, Carolina, J. Paulo Davim, and T.T. Benavides. “Social Media and Inno¬vation: Opportunities and Challenges for Organisations.” In Organisational Innovation in the Digital Age. New York: Springer, 2022.

Mackaay, Ejan. Law and economics for civil law systems. Cheltenham, UK: Edward Elgar Publishing, 2021. (Crossref)

Mathieu, Edouard, Hannah Ritchie, Lucas Rodés-Guirao, Cameron Appel, Char¬lie Giattino, Joe Hasell, Bobbie Macdonald, Saloni Dattani, Diana Beltekian, Esteban Ortiz-Ospina, and Max Roser. “Coronavirus (COVID-19) Vaccina¬tions.” Our World in Data, March 5, 2020. https://ourworldindata.org/cov¬id-vaccinations?country=OWID_WRL.

Max-Planck-Gesellschaft. “Interfering with Patent Protection Means Playing with Fire.” March 15, 2021. https://www.mpg.de/16579491/patent-protec¬tion-vaccines-covid-10-reto-hilty.

Mcallister, Edward, Libby George, and Stephanie Nebehay. “Exclusive: Up to 1 Mil¬lion Covid Vaccines Expired in Nigeria Last Month.” Reuters, December 8, 2021. https://www.reuters.com/business/healthcare-pharmaceuticals/exclusive-up- 1-million-covid-vaccines-wasted-nigeria-last-month-2021–12–08/.

Médecins Sans Frontières Access Campaign. “Compulsory Licenses, the Trips Waiver, and Access to Covid-19 Medical Technologies.” Accessed September 15, 2023. https://msfaccess.org/compulsory-licenses-trips-waiver-and-ac¬cess-covid-19-medical-technologies.

Medicines Law Policy. “Medicines Law & Policy Research and Resources on In¬tellectual Property and Health.” August 21, 2022. https://medicineslawand¬policy.org/.

Moderna. “Moderna’s Updated Patent Pledge.” Accessed September 15, 2023. https://investors.modernatx.com/Statements--Perspectives/Statements--Per¬spectives-Details/2022/Modernas-Updated-Patent-Pledge/default.aspx.

Moon, Suerie, and Ilona Kickbusch. “A Pandemic Treaty for a Fragmented Glob¬al Polity.” The Lancet Public Health 6, no. 6 (2021). https://doi.org/10.1016/ s2468–2667(21)00103–1. (Crossref)

Müller Felix. “The New Council Regulation (EC) No. 1/2003 on the Implemen¬tation of the Rules on Competition.” German Law Journal 5, no. 6 (2004): 721–740. https://doi.org/10.1017/S2071832200012815. (Crossref)

Nikogosian, Haik, and Ilona Kickbusch. “The Case for an International Pandem¬ic Treaty.” BMJ, 2021. https://doi.org/10.1136/bmj.n527. (Crossref)

Nobre, Teresa. “OpenLetter to WIPO: Intellectual Property and COVID-19.” COMMU¬NIA Association, April 16, 2020. https://communia-association.org/2020/04/03/ open-letter-wipo-intellectual-property-covid-19/.

North, Douglass Cecil. Institutions, Institutional change, and Economic Perfor¬mance. Cambridge: Cambridge University Press, 1990.

North, Douglass Cecil. Institutions, Institutional Change, and Economic Perfor¬mance. New York: Cambridge University Press, 2017.

North, Douglass Cecil. Understanding the Process of Economic Change. Prince¬ton, NJ: Princeton Univ. Press, 2010.

O’Donnell, Carl, and Manas Mishra. “Moderna Sees No Impact on COVID-19 Vaccine from Potential Patent Waiver.” Reuters, May 6, 2021. https://www. reuters.com/business/healthcare-pharmaceuticals/moderna-raises-2021- sales-forecast-covid-19-vaccine-192-bln-2021–05–06/.

Odudu, Okeoghene. “Indirect Information Exchange: The Constituent Elements of Hub and Spoke Collusion.” European Competition Journal 7, no. 2 (2011): 205–42. https://doi.org/10.5235/174410511797248324. (Crossref)

Olson, Mancur. Power and Prosperity: Outgrowing Communist and Capitalist Dictatorships. New York: Basic Books, 2000.

Parisi, Francesco, Norbert Schulz, and Ben Depoorter. “Duality in Proper¬ty: Commons and Anticommons.” SSRN Electronic Journal, 2003. https:// doi.org/10.2139/ssrn.224844. (Crossref)

Peabody, John W., Allen Ruby, and Peter Cannon. “The Economics of Orphan Drug Policy in the US.” PharmacoEconomics 8, no. 5 (1995): 374–84. https:// doi.org/10.2165/00019053–199508050–00002. (Crossref)

Peseckyte, Giedre. “MEPs vs Commission in Court over Vaccine Contracts.” EURACTIV, October 29, 2021. https://www.euractiv.com/section/coronavi¬rus/news/meps-vs-commission-in-court-over-vaccine-contracts/.

Petrie, Samuel, Dean Carson, Paul Peters, Anna-Karin Hurtig, Michele LeBlanc, Holly Simpson, Jaymie Barnabe, Mikayla Young, Mara Ostafichuk, Hei¬di Hodge, Justin Gladman, Matilda Smale, and Manueal Gonzalez Gar¬cia. “What a Pandemic Has Taught Us about the Potential for Innovation in Rural Health: Commencing an Ethnography in Canada, the United States, Sweden, and Australia.” Frontiers in Public Health 9 (2021). https:// doi.org/10.3389/fpubh.2021.768624. (Crossref)

Posner, Richard A. Economic Analysis of Law. 8 ed. New York: Wolters Kluwer Law & Business, 2011.

Reiss, Miriam. “High Hopes for Europe’s New Health Emergency and Response Authority.” BMJ, 2022. https://doi.org/10.1136/bmj.o127. (Crossref)

Rimmer, Matthew. “The Race to Patent the SARS Virus: The TRIPS Agreement and Access to Essential Medicines.” Melbourne Journal of International Law 5, no. 2 (2004): 335–74.

Roy, Gopal Krishna. “An Economic Case for Waiving Intellectual Property Rights on Covid Vaccines.” India Quarterly: A Journal of International Affairs 78, no. 1 (2022): 143–47. https://doi.org/10.1177/09749284221078463. (Crossref)

Rutschman, Ana Santos. “IP Preparedness for Outbreak Diseases.” UCLA Law Review 65 (2018): 1200–66.

Rutschman, Ana Santos. “Property and Intellectual Property in Vaccine Mar¬kets.” Texas A&M Journal of Property Law 7, no. 1 (2019): 110–32. https:// doi.org/https://doi.org/10.37419/JPL.V7.I1.4. (Crossref)

Sciacchitano, Salvatore, and Armando Bartolazzi. “Transparency in Negotiation of European Union with Big Pharma on COVID-19 Vaccines.” Frontiers in Public Health 9 (2021). https://doi.org/10.3389/fpubh.2021.647955. (Crossref)

Shalal, Andrea, and Emma Farge. “U.S., EU, India, S. Africa Reach Compromise on COVID Vaccine IP Waiver Text.” Reuters, March 16, 2022. https://www. reuters.com/business/healthcare-pharmaceuticals/us-eu-india-s-africa-reach-tentative-pact-covid-vaccine-ip-waiver-sources-2022–03–15/.

Sibony, Anne-Lise. “The UK COVID-19 Response: A Behavioural Irony?.” European Journal of Risk Regulation 11, no. 2 (2020): 350–57. https:// doi.org/10.1017/err.2020.22. (Crossref)

Tabarrok, Alex. “Patents Are Not the Problem!.” Current Affairs, Economics, Law, Medicine, 2021.

Thambisetty, Siva, Aisling McMahon, Luke McDonagh, Hyo Yoon Kang, and Graham Dutfield. “The Trips Intellectual Property Waiver Proposal: Creat¬ing the Right Incentives in Patent Law and Politics to End the Covid-19 Pan¬demic.” SSRN Electronic Journal, 2021. https://doi.org/10.2139/ssrn.3851737. (Crossref)

The European Consumer Organisation. “Making the Most of EU Advance Pur¬chase of Medicines,” 2021.

The Left. “4 Reasons Why Waiving Trips Is the Best Way to Beat COVID-19.” March 10, 2021. https://left.eu/4-reasons-why-waiving-trips-is-the-best-way-to-beat-covid-19/.

“The territorial impact of Covid-19: Managing the crisis across ... – OECD.” Ac¬cessed September 14, 2023. https://www.oecd.org/coronavirus/policy-re¬ sponses/the-territorial-impact-of-covid-19-managing-the-crisis-across-levels-of-government-d3e314e1/.

Van Lange, Paul A., Jeff Joireman, and Manfred Milinski. “Climate Change: What Psychology Can Offer in Terms of Insights and Solutions.” Cur¬rent Directions in Psychological Science 27, no. 4 (2018): 269–74. https:// doi.org/10.1177/0963721417753945. (Crossref)

Vanneste, Sven, Alain Van Hiel, Francesco Parisi, and Ben Depoorter. “From ‘Tragedy’ to ‘Disaster’: Welfare Effects of Commons and Anticommons Dilemmas.” SSRN Electronic Journal, 2004. https://doi.org/10.2139/ ssrn.548622. (Crossref)

Vinuales, Jorge, Suerie Moon, Ginevra Le Moli, and Gian-Luca Burci. “A Glob¬al Pandemic Treaty Should Aim for Deep Prevention.” The Lancet 397, no. 10287 (2021): 1791–92. https://doi.org/10.1016/s0140-6736(21)00948-x. (Crossref)

World Health Organisation. “Strategy to Achieve Global Covid-19 Vaccination by Mid-2022.” World Health Organisation, 2021. (Crossref)

World Health Organisation. “A Global Pandemic Requires a World Effort to End It – None of Us Will Be Safe until Everyone Is Safe.” September 30, 2020. https://www.who.int/news-room/commentaries/detail/a-global-pandemic-requires-a-world-effort-to-end-it-none-of-us-will-be-safe-until-everyone-is-safe.

World Trade Organisation. “TRIPS Council Hears Initial Reactions to Quad’s Outcome Document on IP COVID-19 Response.” May 6, 2022. https:// www.wto.org/english/news_e/news22_e/trip_06may22_e.htm.

World Trade Organisation. “WTO Analytical Index. WTO Agreement – Arti¬cle IX(3).” June, 2023. https://www.wto.org/english/res_e/publications_e/ai17_e/wto_agree_art9_jur.pdf.

Wouters, Olivier J., Kenneth C. Shadlen, Maximilian Salcher-Konrad, Andrew J. Pollard, Heidi J. Larson, Yot Teerawattananon, and Mark Jit. “Challenges in Ensuring Global Access to COVID-19 Vaccines: Production, Affordability, Allocation, and Deployment.” The Lancet 397, no. 10278 (2021): 1023–34. https://doi.org/10.1016/s0140-6736(21)00306-8. (Crossref)